Toltrazuril Dosage Calculator for Hares (Leverets)

Toltrazuril Dosage Calculator for Leverets [Updated on: 08/31/24 07:14]

Toltrazuril is a broad-spectrum anticoccidial drug that is effective against both gamont & schizont stages of Eimeria spp. It's used to treat coccidia in Leverets (Hares) & Rabbits and is sold as Baycox in most parts of the world. Unfortunately toltrazuril is not readily available in the US. There are a number of concentrations of Baycox (toltrazuril) available: 2.5%, 5%, and 10%. 5% is most commonly used with Hares & Rabbits.

Per the facebook Hare Rescue group the prophylaxis Leveret protocol is 10 mg/kg. They recommend a 9 day dosing protocol (2 days on, 5 days off, 2 days on) dosing at the 10 mg/kg with toltrazuril 5% (50 mg/mL). The calculator will only show the dosing based on the data inputted.

Based on the numbers entered, your leveret of 1 g [0.001 kg] or 0.035 oz [0 lb 0.035 oz] or 0.002 lbs would use a dose of 0 mL [mls] (0 cc), of toltrazuril 5% suspension.

Math for a 1 g or 0.035 oz leveret: 10 mg/kg × 1 g ÷ 50 mg/mL ≈ 0 mL

Using a 2.5% suspension Chicken, Duck, Turkey, Goose, & Pigeon
Day	Dose
1	0 mL [mls]	PO [orally]
2	0 mL [mls]	PO [orally]
3 → 7	0̸
8	0 mL [mls]	PO [orally]
9	0 mL [mls]	PO [orally]

Using a 5% suspension Piglets, Young Cattle, & Rabbits
Day	Dose
1	0 mL [mls]	PO [orally]
2	0 mL [mls]	PO [orally]
3 → 7	0̸
8	0 mL [mls]	PO [orally]
9	0 mL [mls]	PO [orally]

Using a 10% suspension Poultry
Day	Dose
1	0 mL [mls]	PO [orally]
2	0 mL [mls]	PO [orally]
3 → 7	0̸
8	0 mL [mls]	PO [orally]
9	0 mL [mls]	PO [orally]

About U-100 Insulin Syringes
- If you are going to use a U-100 insulin syringe then you MUST remove the needle!!

Dosing a 100 gram leveret with a normal 1 mL syringe can be extreamly challenging! They will need a dose of 0.02 mL of toltrazuril and using a standard 1 mL syringe is near impossible. You can make this task much easier by using a 0.3 cc (0.3 mL) U-100 insulin syringe (with needle removed). These are many times sold as "3/10cc U-100 insulin syringes." This syringe has a barrel size 1/3 the size of a 1 mL barrel.

U-40 syringes have 40 units of insulin in 1 mL
U-100 syringes have 100 units of insulin in 1 mL

Smaller animals and pets (if they need to be given insulin) will use a U-100 or U-40 syringe. Using U-100 syringe makes the conversion of mL of toltrazuril to 'units' much easier! One unit of U-100 (insulin) is 0.01 mL.

Different Sizes of U-100 Syringes...

Example barrel markings...

↑ This is a 1cc (1 mL) U-100 insulin syringe with markings every TWO UNITS.

↑ This is a 1/2cc (0.5 mL) U-100 insulin syringe with markings every ONE UNIT.

↑ These are 3/10cc (0.3 mL) U-100 insulin syringes. Left is half-scale (half-unit markings). Right is whole units with ONE mark for each UNIT.

When converting U-40 insulin to U-100 insulin, follow these guidelines:
U-40 to U-100 Syringe Conversion:

U-40 insulin has 40 units of insulin per milliliter (ml)
U-100 insulin has 100 units of insulin per ml
To convert U-40 units to U-100 units, multiply the U-40 units by 2.5
Example: If you have 10 units of U-40 insulin, it’s equivalent to 25 units in a U-100 syringe (10 × 2.5 = 25)

Volume Conversion:

One unit of U-40 insulin is 0.025 ml in a regular syringe
One unit of U-100 insulin is 0.01 ml in a regular syringe
Always check the syringe packaging to ensure you’re using the correct type (U-40 or U-100)

NOTE: Remember always consult your veterinarian (rabbit savvy) for personalized guidance specific to your rabbit’s needs!!

More information on coccidia from the Hare Rescue group:

What are coccidia and where are they found?

Coccidia are microscopic parasites. They are found in the intestines and liver of animals. The oocysts (eggs of coccidia) are passed in the faeces (droppings).

How does a leveret become infected with coccidia?

Coccidia oocysts are found in food or soil contaminated with infected droppings. The oocyst has a hard shell and can survive on the ground for a long period of time. The oocyst becomes infective 1-4 days after being passed.

What are the clinical signs of coccidiosis?

Watery to mucoid diarrhoea
Weight loss, depression, weakness, dehydration and collapse
Leverets may stop eating
Poor growth and/or death in young or unwell Leverets
Some leverets can carry coccidia and not show any signs of illness
Liver coccidiosis can occur at any age.

How are coccidia identified in Leverets?

A faecal flotation test is done on the droppings to find the oocysts.

What is the treatment for coccidiosis?

Leverets with coccidiosis can be treated with anti-protozoal drugs including Toltrazuril or Trimethoprim sulphonamide. Treatment of secondary bacterial infections may also be necessary. The enclosure should be cleaned thoroughly and all the faeces removed. You can bring it in your home on your shoes! Other pets can bring it in your home.

Syringe info by Arizona Exotic Animal Hospital. If you are writing down any information please read: "Unsafe Medical Abbreviations"

1 mL, mls, or ml (milliliter) = 1 cc or cc³ (cubic centimeter)
1 kg = 2.20462262185 lbs | 1 g = 0.0352739619 oz
"≈" = "almost equal to"
One unit of U-100 (insulin) is 0.01 mL in a regular 1 mL syringe

Cheeky Leveret RSPCA Oak and Furrows.
Brown Hare in hand Lepus europaeus image credit: Yuliiaoleksii.

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[Updated on: 08/31/24 07:14]